VRK1 anticorps (AA 346-396)

N° du produit ABIN7450901

L’anticorps Lapin Polyclonal anti-VRK1 a été validé pour WB et IP. Il convient pour détecter VRK1 dans des échantillons de Humain.

Aperçu rapide pour VRK1 anticorps (AA 346-396) (ABIN7450901)

Antigène: VRK1 (Vaccinia Related Kinase 1 (VRK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VRK1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-VRK1 anticorps

Épitope: AA 346-396

Fonction: Rabbit anti-VRK1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 346 and 396

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur VRK1

Antigène: VRK1 (Vaccinia Related Kinase 1 (VRK1))

Autre désignation: VRK1

Sujet: Background: Vaccinia-related kinase 1 is a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases.VRK1 is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This protein, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN [taken from NCBI Entrez Gene (Gene ID: 7443)].

ID gène: 7443

UniProt: Q99986